Many urban regions in Europe have been hit hard by the economic crisis, but some regions have been more resilient than others. The question is why. This project investigates how European regions have responded to economic shocks, how successful they have been in developing new industries, and whether economic resilience goes hand in hand with increased social well-being. Furthermore there will be researched if regions that are strongly linked with other regions are more resilient, and which institutions and policy approaches have been more beneficial. These questions are investigated in quantitative analyses of regions in EU27, and a more in-depth analysis of 6 regions.